In most cases, kidney failure is caused by other health problems that have done permanent damage (harm) to your kidneys little by little, over time.

When your kidneys are damaged, they may not work as well as they should. If the damage to your kidneys continues to get worse and your kidneys are less and less able to do their job, you have chronic kidney disease.

Kidney failure is the last (most severe) stage of chronic kidney disease. This is why kidney failure is also called end-stage renal disease, or ESRD for short.
Diabetes is the most common cause of ESRD. High blood pressure is the second most common cause of ESRD. Other problems that can cause kidney failure include:

Autoimmune diseases, such as
lupus and IgA nephropathy
Genetic diseases (diseases you are born with), such as polycystic kidney disease
Nephrotic syndrome
Urinary tract problems
Sometimes the kidneys can stop working very suddenly (within two days). This type of kidney failure is called acute kidney injury or acute renal failure. Common causes of acute renal failure include:

Heart attack
Illegal drug use and drug abuse
Not enough blood flowing to the kidneys
Urinary tract problems
This type of kidney failure is not always permanent. Your kidneys may go back to normal or almost normal with treatment and if you do not have other serious health problems.

Having one of the health problems that can lead to kidney failure does not mean that you will definitely have kidney failure.

Living a healthy lifestyle and
working with your doctor to control these health problems can help your kidneys work for as long as possible.

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Symptoms of chronic kidney disease
Chronic kidney disease (CKD) usually gets worse slowly, and symptoms may not appear until your kidneys are badly damaged.

In the late stages of CKD, as you are nearing kidney failure (ESRD), you may notice symptoms that are caused by waste and extra fluid building up in your body.

You may notice one or more of the following symptoms if your kidneys are beginning to fail:

Itching
Muscle cramps
Nausea and vomiting
Not feeling hungry
Swelling in your feet and ankles
Too much urine (pee) or not enough urine
Trouble catching your breath
Trouble sleeping
If your kidneys stop working suddenly (acute kidney failure), you may notice one or more of the following symptoms:

Abdominal (belly) pain
Back pain
Diarrhoea
Fever
Nosebleeds
Rash
Vomiting
Having one or more of any of the symptoms above may be a sign of serious kidney problems.

If you notice any of these symptoms, you should contact your doctor right away.Kidneyfund.org